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Before taking busulfan tablets, you should know that the immune system is suppressed, so you may have trouble fighting infections. In addition, the tablet busulfan may put you at higher risk for developing a severe form of anemia known as aplastic anemia. Certain drugs, such as acetaminophen, metronidazole and itraconazole may increase the risk of serious side effects from the tablets busulfan. There are also some things you should tell your doctor before they prescribe tablet busulfan for you. For one thing, let your doctor know if you are pregnant, planning to become pregnant or if you are breastfeeding. In addition, tell your doctor if you have a history of seizures or head injury, problems with the blood or bone marrow depression function.
Side effects may include pain in the joints, muscles, back or chest, faster than normal heartbeat, high blood pressure, blood clotting gastrointestinal symptoms such as constipation, diarrhea, loss of indigestion, loss of appetite, nausea or rectal disorder, increased levels of sugar blood, nosebleeds, cold or flu symptoms, such as coughs, colds or sinus inflammation, asthma, lung disorders, itching, insomnia, rash, hiccups, anxiety, dizziness, headache, confusion, dry mouth, changes in menstrual cycle; fatigue, weakness, rash, and flushing. In addition, the general effect, but generally mild side listed above, there are a number of severe side effects.
Contact your doctor immediately if you experience severe allergic reactions, abnormal fatigue, abdominal pain, vomiting, fever, chills or sore throat, shortness of breath, excessive sweating, unusual bleeding or bruising, irregular heartbeat, congestion, depression , inability to fight infections, vision changes, missed menstrual periods; pale skin, hallucinations, rapid weight loss, cough that will not go away, and loss of consciousness. There also may be other side effects not listed here. If you experience other bothersome symptoms while you are taking busulfan tablets, you should let your doctor know. You should contact your doctor if any of the more common, but minor, side effects start to bother you or if they will not go away.